Main areas of work

• study of bone regeneration;
• evaluation of tissue response to new synthetic and biological implant materials;
• study of the factors of degeneration of the intervertebral disc and articular cartilage;
• studying the mechanisms of osteoporosis and arthrosis development, ways to correct the disorders;
• the role of muscle tissue in the development of degenerative diseases of the spine;
• muscle condition in conditions of bone regeneration disorders;
• pathological diagnostics of diseases of the skeletal and muscular systems, tumor lesions of bones and joints;
• bone mineral density studies – standard examinations and determination of bone tissue condition in the periprosthetic area, quantitative assessment of vertebral deformities.

The Laboratory is certified in accordance with the requirements of DSTU ISO 10012:2005 (Certificate No. 01-0018/2023 dated 14.03.2023) and conducts basic and applied research on key issues of traumatology and orthopedics.

The laboratory of connective tissue morphology is equipped with modern microscopes: Olympus BX63 with fluorescence module, digital camera DP73 (Olympus) and software “Cell Sens Dimension 1.8.1” (2013); Olympus BX53 with polarization module, AxioStar (Carl Zeiss), which provide excellent visualization and analysis of histological material by light, polarization and fluorescence microscopy. Cell Sens Dimension 1.8.1 software (Olympus, 2013) allows for morphometric studies, photography and digital storage of the results.

The transmission electron microscope EMV-100BR allows for ultramicroscopic studies.

The study of bone mineral density is performed by dual-energy X-ray absorptiometry on the Explorer QDR W bone densitometer (Hologic).

The laboratory staff is proficient in light, polarization, fluorescence and electron microscopy methods to study the structural features of body tissues, including bone. They are highly qualified to diagnose tumors and tumor-like diseases of bones and joints.

During the period from 2019 to 2023, the laboratory staff published 42 scientific articles, including 29 articles (70%) in journals indexed in Scopus / Web of Science; 21 papers in the proceedings of conferences and congresses, and 1 patent. Scientific articles have been published in such foreign professional journals as the Journal of Orthopaedic Surgery and Research, World journal of Orthopaedics, Journal of Biomedical Materials Research Part B: Applied Biomaterials, Journal of bone and joint surgery. American volume, Romanian Journal of Morphology and Embryology, Actualizaciones en Osteologia. Also in Ukrainian leading scientific journals: Orthopedics, Traumatology and Prosthetics, Zaporizhzhya Medical Journal, Ukrainian Journal of Radiology and Oncology, Regulatory Mechanisms in Biosystems, Pathology, Problems of Endocrine Pathology.