Scientific Activities

State Institution “Sytenko Institute of Spine and Joint Pathology, NAMS of Ukraine” – is the oldest scientific and treatment establishment in Ukraine, created in 1907.

The staff of the Institute includes 23 Full Doctors of Sciences with 7 Professors among them, and 53 PhDs.

SI “Sytenko Institute for Spine and Joints Pathology of the NAMS of Ukraine” is a head scientific institution dealing with problems of the spine and joints pathology among all institutions of the Academy of Medical Sciences of Ukraine and provides proper co-ordinating work on scientific research and organizing measures in this field.

Privileged research directions of the institution:

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experimental and theoretical investigation of the problems of diagnostics, conceptual foresight of the states of diseases and injuries of the joints and spine (adults and children), complications preventing, working-out of new treatment technologies (including surgical), working-out of the techniques of patients rehabilitation according to the different stages of treatment;

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investigation of the possibilities and usage of surgical treatment of benign and malignant bone tumors with the focus on the organ preserving surgery on spine and extremities;

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working-out of new bioinert implant materials for the plastic repair of vertebral bone defects;

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development of advanced methods of tissue engineering, directed on the restoration of function of loco-motor apparatus, particularly, in the case of injury and disease of spine and joints;

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working-out of new and improvement of existing methods for prevention, diagnostics and treatment of disabling diseases and injuries of spine and joints in children.

Fundamental Researches in Theoretical and Clinical Medicine

To study the possibilities of biotechnology for the correction of failed reparative osteogenesis to prevent nonunion and pseudoarthrosis

Scientific Supervisor: Prof. M. Korzh DMSc

Responsible Investigators: MD P. Vorontsov PhD, V. Maltseva PhD

Implementation period: 2023-2025

To investigate the pathogenetic relationship between hemostasis disorders and inflammatory-destructive changes in degenerative diseases, post-traumatic and combat injuries of large joints

Scientific Supervisor: Prof. V. Filipenko DMSc

Responsible Investigator: V. Tulyakov DPhSc

Implementation period: 2023-2025

To optimize the perioperative management of surgical interventions in patients with the consequences of combat injuries and orthopedic pathology combined with disorders of the cardiovascular and nervous systems

Scientific Supervisor: Prof. M. Korzh DMSc

Responsible Investigators: M. Lyzohub DMSc, MD K. Lyzohub PhD

Implementation period: 2024-2026

Applied Researches

To develop a complex of diagnostic-treatmental measures for internal-rotary contracture of the shoulder joint in children with obstetrical brachial plexus palsy of Duchenne-Erb

Scientific Supervisor: Prof. S. Khmyzov DMSc

Responsible Investigator: A. Hrytsenko

Implementation period: 2023-2025

To improve the diagnosis and treatment of new compression fractures of the vertebrae of the thoracic and lumbar spine in patients with diffuse osteoporosis after vertebroplasty

Scientific Supervisor: V. Kutsenko DMSc

Responsible Investigator: A. Popov DMSc

Implementation period: 2024-2025

To improve the diagnosis and treatment of degenerative diseases of the lumbar spine in military personnel (clinical and experimental study)

Scientific Supervisor: A. Popov DMSc

Responsible Investigator: MD O. Perfiliev PhD

Implementation period: 2024-2026

To develop a method of physical rehabilitation after endoscopic surgical treatment of herniated intervertebral discs of the lumbar spine for civilians and military personnel under the conditions of various clinical course variants and various external loads on the musculoskeletal system

Scientific Supervisor: V. Kolesnichenko DMSc

Responsible Investigator: M. Holbaum

Implementation period: 2024-2026

To develop methods of rational treatment of gunshot fractures of the limbs based on the study of the tissue regeneration process

Scientific Supervisor: Prof. M. Korzh DMSc

Responsible Investigator: Prof. O. Popsuishapka DMSc

Implementation period: 2024-2026

To develop methods for the reconstruction of post-resection and post-traumatic bone and joint defects in patients with primary tumors and traumatic injuries of the pelvic bones

Scientific Supervisor: S. Bondarenko DMSc

Responsible Investigator: I. Skoryk PhD

Implementation period: 2024-2026

To investigate the possibilities of osseointegrative limb prosthetics in patients with combat trauma consequences

Scientific Supervisor: S. Bondarenko DMSc

Responsible Investigator: O. Haluzynskyi PhD

Implementation period: 2025-2027

To investigate the effectiveness of the use of biological therapy methods in the treatment of patients with defects of long bones after combat trauma

Scientific Supervisor: MD K. Romanenko PhD

Responsible Investigator: MD Ya. Doluda PhD

Implementation period: 2025-2026

Fundamental researches in the theoretical and clinical medicine

«To study the possibilities of biotechnology for the correction of failed reparative osteogenesis to prevent nonunion and pseudoarthrosis». (2023-2025)

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — MD PhD P.Vorontsov

«To investigate the pathogenetic relationship between hemostasis disorders and inflammatory-destructive changes in degenerative diseases, post-traumatic and combat injuries of large joints» (2023-2025)

Scietific Director — prof. V.Filipenko

Principle Investigator — D.Ph.Sc. V.Tulyakov

«To optimize the perioperative management of surgical interventions in patients with the consequences of combat injuries and orthopedic pathology combined with disorders of the cardiovascular and nervous systems» (2024-2026)

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — DMSc M.Lyzohub, PhD K.Lyzohub

Applied researches

«To develop a complex of diagnostic-treatmental measures for internal-rotary contracture of the shoulder joint in children with obstetrical brachial plexus palsy of Duchenne-Erb » (2023-2025).

Scietific Director — prof. S.Khmyzov, D.Med.Sc.

Principle Investigators — A.Hrytsenko

«To improve the diagnosis and treatment of new compression fractures of the vertebrae of the thoracic and lumbar spine in patients with diffuse osteoporosis after vertebroplasty (2024-2025)

Scietific Director — D.Med.Sc. V.Kutsenko

Principle Investigators — D.Med.Sc A.Popov

«To improve the diagnosis and treatment of degenerative diseases of the lumbar spine in military personnel (clinical and experimental study)» (2024-2026)

Scietific Director — D.Med.Sc. A.Popov

Principle Investigators — MD PhD О.Barkov

«To develop a method of physical rehabilitation after endoscopic surgical treatment of herniated intervertebral discs of the lumbar spine for civilians and military personnel under the conditions of various clinical course variants and various external loads on the musculoskeletal system» (2024-2026)

Scietific Director — D.Med.Sc. V.Kolesnichenko

Principle Investigator — M.Holbaum

«To develop methods of rational treatment of gunshot fractures of the limbs based on the study of the tissue regeneration process)» (2024-2026)

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigator — prof. O. Popsuishapka, D.Med.Sc.

«To develop methods for the reconstruction of post-resection and post-traumatic bone and joint defects in patients with primary tumors and traumatic of the pelvic bones)» (2024-2026)

Scietific Director — prof, DMSc S. Bondarenko

Principle Investigator — PhD I.Skoryk

Fundamental researches in the theoretical and clinical medicine

To study the possibilities of biotechnology for the correction of failed reparative osteogenesis to prevent nonunion and pseudoarthrosis.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigator — MD PhD P. Vorontsov

To investigate the pathogenetic relationship between hemostasis disorders and inflammatory-destructive changes in degenerative diseases, post-traumatic and combat injuries of large joints.

Scietific Director — prof. V.Filipenko, D.Med.Sc

Principle Investigator — D.Ph.Sc. V.Tulyakov

Applied researches

To study the features of functional disorders in the combined pathology of the lumbar spine and hip joint and to develop tactics and requirements for the surgical treatment of these patients.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — D.Med.Sc. K.Popsuishapka, MD PhD O.Pidgaiska

To study the pathophysiological mechanisms of hemodynamic and neurological reactions caused by the type of anesthesia and intraoperative position of the patient’s body during spine surgery.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigators — D.Med.Sc. M.Lyzohub, MD PhD I.Kotulsky

Develop tactics of rational spinal fusion for the treatment of patients with vertebral fractures of the thoracic spine.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigators — D.Med.Sc K.Popsuishapka, S.Teslenko

To develop differentiated approaches of surgical treatment of patients with pelvic bone tumors.

Scietific Director — prof. O.Vyrva, D.Med.Sc.

Principle Investigator — MD PhD R.Malyk

Improve methods of surgical treatment of patients with degenerative-dystrophic diseases of the lumbar spine using the latest technologies.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — MD PhD O.Barkov

To study the mechanisms of formation of immobilization contractures and to investigate the influence of low-frequency vibration on the restoration of joint function.

Scietific Director — prof. O.Tyazhelov ,D.Med.Sc.

Principle Investigator — M. Karpisky

To develop a complex of diagnostic-treatmental measures for internal-rotary contracture of the shoulder joint in children with obstetrical brachial plexus palsy of Duchenne-Erb.

Scietific Director — prof. S.Khmyzov,D.Med.Sc.

Principle Investigator — A.Hrytsenko

Fundamental researches in the theoretical and clinical medicine

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — D.Med.Sc. A.Skidanov

To study the mechanisms of optimization of bone repair depending on the recipient’s age under the conditions of allogeneic bone grafts application in combination with mesenchymal stem cells and biologically active blood plasma factors.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — MD PhD P. Vorontsov, PhD BioSc. N. Ashukina

Experimental study of bone tissue reaction and biomechanical properties of “implant-bone”system at application of innovative 3D-printed materials made of polilactide acid and trabecular titanium.

Scietific Director — prof. V.Filipenko, D.Med.Sc.

Principle Investigator — MD PhD O.Pidgaiska

Applied researches

Develop a comprehensive approach to treatment of congenital pseudoarthrosis of the tibia and fibula in children.

Scietific Director — prof. S.Khmyzov,D.Med.Sc.

Principle Investigator — Ye.Katsalap

To study the features of functional disorders in the combined pathology of the lumbar spine and hip joint and to develop tactics and requirements for the surgical treatment of these patients.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — PhD in MedSci K.Popsuishapka, MD PhD O.Pidgaiska

To study the pathophysiological mechanisms of hemodynamic and neurological reactions caused by the type of anesthesia and intraoperative position of the patient’s body during spine surgery.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigators — D.Med.Sc. M.Lyzohub, PhD in MedSci MD PhD I.Kotulsky

Develop tactics of rational spinal fusion for the treatment of patients with vertebral fractures of the thoracic spine.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigators — PhD in MedSci K.Popsuishapka, S.Teslenko

To develop differentiated approaches of surgical treatment of patients with pelvic bone tumors.

Scietific Director — prof. O.Vyrva, D.Med.Sc.

Principle Investigator — MD PhD R.Malyk

Improve methods of surgical treatment of patients with degenerative-dystrophic diseases of the lumbar spine using the latest technologies.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — MD PhD O.Barkov

To study the mechanisms of formation of immobilization contractures and to investigate the influence of low-frequency vibration on the restoration of joint function.

Scietific Director — prof. O.Tyazhelov ,D.Med.Sc.

Principle Investigator — M. Karpisky

Develop a set of medical and organizational measures to improve the system of medical care for victims of road accidents.

Scietific Director — prof. V.Tankut D.Med.Sc.

Principle Investigator — I. Golubeva

Fundamental researches in the theoretical and clinical medicine

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — D.Med.Sc. A.Skidanov

To study the mechanisms of optimization of bone repair depending on the recipient’s age under the conditions of allogeneic bone grafts application in combination with mesenchymal stem cells and biologically active blood plasma factors.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — MD PhD P. Vorontsov, PhD BioSc. N. Ashukina

Experimental study of bone tissue reaction and biomechanical properties of “implant-bone”system at application of innovative 3D-printed materials made of polilactide acid and trabecular titanium.

Scietific Director — prof.V.Filipenko, D.Med.Sc.

Principle Investigator — MD PhD O.Pidgaiska

Applied researches

To study the main errors and complications of transpedicular fixation in spine surgery and to develop measures for their prevention and treatment.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — MD PhD O.Barkov

To study the biomechanical features of the standing and walking function of a man after hip arthroplasty.

Scietific Director — prof. O.Tyazhelov ,D.Med.Sc.

Principle Investigator — M. Karpisky

To work out the system of organizational arrangements, curative and preventive services, to decrease negative consequences of the traumatic and combat injuries of long bones.

Scietific Director — prof. M.Korzh,D.Med.Sc.

Principle Investigator — MD PhD K.Romanenko

Develop a comprehensive approach to treatment of congenital pseudoarthrosis of the tibia and fibula in children.

Scietific Director — prof. S.Khmyzov,D.Med.Sc.

Principle Investigator — Ye.Katsalap

To study the features of functional disorders in the combined pathology of the lumbar spine and hip joint and to develop tactics and requirements for the surgical treatment of these patients.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — PhD in MedSci K.Popsuishapka, MD PhD O.Pidgaiska

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — D.Med.Sc. A.Skidanov

To study the pathophysiological mechanisms of hemodynamic and neurological reactions caused by the type of anesthesia and intraoperative position of the patient’s body during spine surgery.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigators — D.Med.Sc. M.Lyzohub, PhD in MedSci MD PhD I.Kotulsky

Develop tactics of rational spinal fusion for the treatment of patients with vertebral fractures of the thoracic spine.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigators — PhD in MedSci K.Popsuishapka, S.Teslenko

To develop differentiated approaches of surgical treatment of patients with pelvic bone tumors.

Scietific Director — prof. O.Vyrva, D.Med.Sc.

Principle Investigator — MD PhD R.Malyk

Fundamental researches in the theoretical and clinical medicine

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — D.Med.Sc. A.Skidanov

To study the mechanisms of optimization of bone repair depending on the recipient’s age under the conditions of allogeneic bone grafts application in combination with mesenchymal stem cells and biologically active blood plasma factors.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — MD PhD P. Vorontsov, PhD BioSc. N. Ashukina

Experimental study of bone tissue reaction and biomechanical properties of “implant-bone”system at application of innovative 3D-printed materials made of polilactide acid and trabecular titanium.

Scietific Director — prof. V.Filipenko, D.Med.Sc.

Principle Investigator — MD PhD O.Pidgaiska

Applied researches

Develop a concept of treatment of traumatic and humidified burst bodies of the thoracal and lumbar spine.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — PhD in MedSci K.Popsuishapka

Improve the diagnosis and surgical treatment of patients with hematopoietic and metastatic lesions of thoracic and lumbar spine.

Scietific Director — D.Med.Sc. V.Kutsenko

Principle Investigator — MD PhD A.Popov

To investigate the causes of development and improve the methods of prevention and treatment of contracture of the knee joints in gonarthrosis, as consequences of traumatic injuries and after total knee arthroplasty.

Scietific Director — prof.V.Filipenko, D.Med.Sc.

Principle Investigator — MD PhD O.Tankut

Develop methods bioreсonstrution defects of long bones and joints in the surgical treatment of bone tumors.

Scietific Director — prof. O.Vyrva, D.Med.Sc.

Principle Investigator — MD PhD Ya.Holovina

To study the main errors and complications of transpedicular fixation in spine surgery and to develop measures for their prevention and treatment.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — MD PhD O.Barkov

To study the biomechanical features of the standing and walking function of a man after hip arthroplasty.

Scietific Director — prof. O.Tyazhelov ,D.Med.Sc.

Principle Investigator — M. Karpisky

To work out the system of organizational arrangements, curative and preventive services, to decrease negative consequences of the traumatic and combat injuries of long bones.

Scietific Director — prof. M.Korzh,D.Med.Sc.

Principle Investigator — MD PhD K.Romanenko

Develop a comprehensive approach to treatment of congenital pseudoarthrosis of the tibia and fibula in children.

Scietific Director — prof. S.Khmyzov,D.Med.Sc.

Principle Investigator — Ye.Katsalap

Fundamental researches in the theoretical and clinical medicine

To explore common links in the mechanism of pathogenesis of osteoporosis, osteoarthrosos and spine osteochondrosis for substantiation of approaches to improve the efficiency of diagnosis, prevention and treatment.

Scietific Director — prof. M.Korzh , D.Med.Sc.

Principle Investigators — prof. V.Filipenko, D.Med.Sc., PhD BioSc. N. Ashukina

To investigate the pathogenetic mehanisms of juvenile osteochondropathic kyphosis formation (Scheueremann’s disease).

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigators — MD PhD I.Kotulsky, prof. S.Khmyzov, D.Med.Sc

To study the reparative properties of bioengineered structures on the basis of bone allografts and xenografts that are saturated with stem cells and growth factors.

Scietific Director — prof. M.Korzh, D.Med.Sc.

Principle Investigator — MD PhD P. Vorontsov

Applied researches

Develop a concept of treatment of traumatic and humidified burst bodies of the thoracal and lumbar spine.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — PhD in MedSci K.Popsuishapka

Improve the diagnosis and surgical treatment of patients with hematopoietic and metastatic lesions of thoracic and lumbar spine.

Scietific Director — D.Med.Sc. V.Kutsenko

Principle Investigator — MD PhD A.Popov

To investigate the causes of development and improve the methods of prevention and treatment of contracture of the knee joints in gonarthrosis, as consequences of traumatic injuries and after total knee arthroplasty.

Scietific Director — prof.V.Filipenko, D.Med.Sc.

Principle Investigator — MD PhD O.Tankut

Develop methods bioreсonstrution defects of long bones and joints in the surgical treatment of bone tumors.

Scietific Director — prof. O.Vyrva, D.Med.Sc.

Principle Investigator — MD PhD Ya.Holovina

To study the main errors and complications of transpedicular fixation in spine surgery and to develop measures for their prevention and treatment.

Scietific Director — prof. V.Radchenko, D.Med.Sc.

Principle Investigator — MD PhD O.Barkov

To study the biomechanical features of the standing and walking function of a man after hip arthroplasty.

Scietific Director — prof. O.Tyazhelov ,D.Med.Sc.

Principle Investigator — M. Karpisky

To work out the system of organizational arrangements, curative and preventive services, to decrease negative consequences of the traumatic and combat injuries of long bones.

Scietific Director — prof. M.Korzh,D.Med.Sc.

Principle Investigator — MD PhD K.Romanenko

1.		To study mechanisms of osteopenia and osteoporosis development in the conditions of traumatic injuries of long bones
2.		To research features of pathogenesis in circadian rtythms of transitory low back pain
3.		To develop a system of limb-salvage surgery in patients with malignant tumors of long bones.
4.		Features of formation of a trajectory of moving of the general centre of weights of the person in the course of support of a vertical pose for diagnostics of infringements of function of oporno-impellent system
5.		To study the bone rebuilding in exteriorization zone of titanic implants under the influence of ultrasound
6.		Ground and development the methods of diagnostic and the surgical treatment of congenital anomaly of hand and forearm in children.

1.	0108U 001072	To investigate reparative osteogenesis and changes in the tissues of injured segment in the conditions of multiplane posttraumatic deformity of extremity (experimental-clinical investigation)
2.	0108U 001073	To research the monoaminergic and cholinergic effects in the cases of pain syndroms with different origin in locomotor system (08.01-10.12)
3.	0110U 00____	To study mechanisms of development of lumbar degenerate stenosis (10.01-12.12)
4.	0110U 00____	To study the state of adjacent motor vertebral segments after fusion (10.01-12.12)
5.	0108U 001074	To treat new methods of osteosynthesis with carbon implants for metaphyseal and metadiaphyseal fractures of long bones for elder people (08.01-10.12)
6.	0108U 000391	To study the influens of complex using low level infra-red radiation and medical drugs on ostearthrosis progression (08.01-10.12)
7.	0108U 1076	To develop new methods of endoprosthetic replacement of bones and joints defects in the treatment of bone tumors of the upper limbs (08.01-10.12)
8.	0109U 002015	To study mechanisms of progressing lumbar spondylolistesis and to develop criterions of forecasting of its course and consequences (09.01-11.12)
9.	0109U 002014	Adult scoliosis diagnostic and treatment optimization
10.	0109U 002016	To develop application technology of hip endoprosthesis with a singl-crystal corundum (09.01-11.12)
11.	0110U 00____	To explore intercommunication between violations of bone and cartilaginous tissues metabolism and system of haemostase at patients with the different stages of large joints osteoarthrosis for warning of the hypercoagulabilitys states development (10.01-12.12)
12.	0110U 00____	To study the condition and dynamics of disability connected with degenerative spine and elaborate a comprehensive complex of activites in order to prophylaxis of disability (10.01-12.12)
13.	0109U	Ground and development the methods of diagnostic and the prevention surgical treatment of spastic hip joint instability in children with cerebral palsy (09.01-11.12)
14.		Bactericidal coverings for orthopedy and traumatology (08.02-10.02)

1.	0107U 000106	To study the mechanisms of development and age pecularities of degenerative diseases of the spine (07.01 – 09.12)
2.	0107U 000107	To study experimentally the structure and mechanical properties of the adjacent spine segments in different variants of biomaterials implantation into the vertebra (07.01 – 09.12)
3.	0108U 001072	To investigate reparative osteogenesis and changes in the tissues of injured segment in the conditions of multiplane posttraumatic deformity of extremity (experimental-clinical investigation)(08.01-10.12)
4.	0108U 001073	To research the monoaminergic and cholinergic effects in the cases of pain syndroms with different origin in locomotor system (08.01-10.12)
5.	0107U 000109	To study diagnostic significance of glycoproteins and glycosaminglycanes metabolic indeces fior the flow of large joints osteoartrosis (07.01-09.12)
6.	0107U 000111	To study a degree and criteria of disability in the diseases of major joints and develop complex mesurements for its prevention. (07.01-09.12)
7.	0108U 001074	To treat new methods of osteosynthesis with carbon implants for metaphyseal and metadiaphyseal fractures of long bones for elder people (08.01-10.12)
8.	0108U 000391	To study the influens of complex using low level infra-red radiation and medical drugs on ostearthrosis progression (08.01-10.12)
9.	0108U 1076	To develop new methods of endoprosthetic replacement of bones and joints defects in the treatment of bone tumors of the upper limbs (08.01-10.12)
10.	0109U 002015	To study mechanisms of progressing lumbar spondylolistesis and to develop criterions of forecasting of its course and consequences (09.01-11.12)
11.	0109U 002014	Adult scoliosis diagnostic and treatment optimization (09.01-11.12)
12.	0109U 002016	To develop application technology of hip endoprosthesis with a singl-crystal corundum (09.01-11.12)
13.	0107U 000112	To study the perculiarities of the postoperative hip joints development in children with displastic joints pathology, to develop and justify new methods of surgical intervention and modify the ones already existed (07.01-09.12)
14.	0109U	Ground and development the methods of diagnostic and the prevention surgical treatment of spastic hip joint instability in children with cerebral palsy (09.01-11.12)
15.		Bactericidal coverings for orthopedy and traumatology (08.02-10.02)

1.		Development and improvement of complex of diagnostic and treatment events of the cervical spine deformations. (2006-2008)
2.		To develop a system of the surgical treatment of juvenile scoliosis. (2006-2008)
3.		To study experimentally the structure and mechanical properties of the adjacent spine segments in different variants of biomaterials implantation into the vertebra. 2007-2009
4.		To study the mechanisms of development and age pecularities of degenerative diseases of the spine. 2007-2009
5.		To develop new methods of the total hip joint endoprosthetics in the acetabulum defects. 2007-2008
6.		To study diagnostic significance of glycoproteins and glycosaminglycanes metabolic indeces fior the flow of large joints osteoartrosis. 2007-2009
7.		To develop methods of surgical correction of the knee joint deformation on the grounds of topographical studies of the binite-element model voltages. 2007-2009
8.		To study a degree and criteria of disability in the diseases of major joints and develop complex mesurements for its prevention. 2007-2009
9.		To study the perculiarities of the postoperative hip joints development in children with displastic joints pathology, to develop and justify new methods of surgical intervention and modify the ones already existed. 2007-2009
10.		To investigate reparative osteogenesis and changes in the tissues of injured segment in the conditions of multiplane posttraumatic deformity of extremity (experimental-clinical investigation)2008-2010
11.		To research the monoaminergic and cholinergic effects in the cases of pain syndroms with different origin in locomotor system 2008-2010
12.		To treat new methods of osteosynthesis with carbon implants for metaphyseal and metadiaphyseal fractures of long bones for elder people 2008-2010
13.		To study the influens of complex using low level infra-red radiation and medical drugs on ostearthrosis progression. 2008-2010
14.		To develop new methods of endoprosthetic replacement of bones and joints defects in the treatment of bone tumors of the upper limbs. 2008-2010

1.		To research pathogenesis and to improve methods diagnostics and conservative treatment for avascular necrosis of the femoral head in adults. (2005-2007).
2.		To research of results of individual endoprosthetics of long bone and joint postresection defects in the system of complex treatment of bone tumors. (2005-2007).
3.		To study of changes of aged patients on osteoartrosis clinical course in application of pelotherapy. (2005-2007).
4.	3174	Development of new types of intraosseous fixative devices with a removable and biodegradable coating. (2004-2007).
5.		Development and improvement of complex of diagnostic and treatment events of the cervical spine deformations. (2006-2008)
6.		To develop a system of the surgical treatment of juvenile scoliosis. (2006-2008)
7.		To study experimentally the structure and mechanical properties of the adjacent spine segments in different variants of biomaterials implantation into the vertebra. 2007-2009
8.		To study the mechanisms of development and age pecularities of degenerative diseases of the spine. 2007-2009
9.		To study the bone regeneration at the traumatic damages at endocrine osteoporosis. (2005-2007).
10.		To develop new methods of the total hip joint endoprosthetics in the acetabulum defects. 2007-2008
11.		To study diagnostic significance of glycoproteins and glycosaminglycanes metabolic indeces fior the flow of large joints osteoartrosis. 2007-2009
12.		To develop methods of surgical correction of the knee joint deformation on the grounds of topographical studies of the binite-element model voltages. 2007-2009
13.		To study a degree and criteria of disability in the diseases of major joints and develop complex mesurements for its prevention. 2007-2009
14.		To study the perculiarities of the postoperative hip joints development in children with displastic joints pathology, to develop and justify new methods of surgical intervention and modify the ones already existed. 2007-2009

1.		Research osteointegration processes at plastics of bone defects by calcium phosphate ceramics of different structure and composition. (2004-2006).
2.		Develop the grafts on the base of connective tissue cells grown on the biodegradable matrixes for optimization of the repair process of the intervertebral disc. (2004-2006).
3.		Study of genesis of degenerative and dysplastic deformities of lumbar spine in adult, work out methods of early diagnosis, prognosis and surgical treatment. (2004-2006).
4.		To develop new high technological methods of osteosynthesis and substitution of bone defects in elderly patients with carbon and ceramic implants. (2004-2006).
5.		To study the disability condition connected with spine diseases and elaborate a comprehensive complex of activities in order to reduce the number of disability value. (2004-2006).
6.		To develop technology of early diagnostics, treatment and prophylaxis of dysplastic spine and joints diseases resulting in invalidism in young age. (2003-2006).
7.		Design, making and clinical using of new native artificial hip joint with sapphire-sapphire friction pair. (2003-2006).
8.	1913	Development and clinical approval of sapphire-metallic hip joint endoprothesis. (2002-2005).

1.		To study the bone regeneration at the traumatic damages at endocrine osteoporosis. (2005-2007).
2.		To research pathogenesis and to improve methods diagnostics and conservative treatment for avascular necrosis of the femoral head in adults. (2005-2007).
3.		Research osteointegration processes at plastics of bone defects by calcium phosphate ceramics of different structure and composition. (2004-2006).
4.		Develop the grafts on the base of connective tissue cells grown on the biodegradable matrixes for optimization of the repair process of the intervertebral disc. (2004-2006).
5.		Development of new and improvement of existing methods of operative management of spinal injuries and their consequents. (2003-2005).
6.		Investigate the change made by spinal orthosis in scoliotic deformation in children and adolescent for improvement of medical effect. (2003-2005).
7.		Study of genesis of degenerative and dysplastic deformities of lumbar spine in adult, work out methods of early diagnosis, prognosis and surgical treatment. (2004-2006).
8.		To develop new high technological methods of osteosynthesis and substitution of bone defects in elderly patients with carbon and ceramic implants. (2004-2006).
9.		To study the disability condition connected with spine diseases and elaborate a comprehensive complex of activities in order to reduce the number of disability value. (2004-2006).
10.		To research of results of individual endoprosthetics of long bone and joint postresection defects in the system of complex treatment of bone tumors. (2005-2007).
11.		To study of changes of aged patients on osteoartrosis clinical course in application of pelotherapy. (2005-2007).
12.		To develop technology of early diagnostics, treatment and prophylaxis of dysplastic spine and joints diseases resulting in invalidism in young age. (2003-2006).
13.		Design, making and clinical using of new native artificial hip joint with sapphire-sapphire friction pair. (2003-2006).
14.	1913	Development and clinical approval of sapphire-metallic hip joint endoprothesis. (2002-2005).
15.	3174	Development of new types of intraosseous fixative devices with a removable and biodegradable coating. (2004-2007).

1.		Develop the grafts on the base of connective tissue cells grown on the biodegradable matrixes for optimization of the repair process of the intervertebral disc. (2004-2006)
2.		Research osteointegration processes at plastics of bone defects by calcium phosphate ceramics of different structure and composition. (2004-2006).
3.		Development of new and improvement of existing methods of operative management of spinal injuries and their consequents. (2003-2005).
4.		Investigate the change made by spinal orthosis in scoliotic deformation in children and adolescent for improvement of medical effect. (2003-2005).
5.	1913	Development and clinical approval of sapphire-metallic hip joint endoprothesis. (2002-2005).
6.	3174	Development of new types of intraosseous fixative devices with a removable and biodegradable coating. (2004-2007).
7.		Study of genesis of degenerative and dysplastic deformities of lumbar spine in adult, work out methods of early diagnosis, prognosis and surgical treatment. (2004-2006).
8.		To develop new high technological methods of osteosynthesis and substitution of bone defects in elderly patients with carbon and ceramic implants. (2004-2006).
9.		To study the disability condition connected with spine diseases and elaborate a comprehensive complex of activities in order to reduce the number of disability value. (2004-2006).
10.		To develop technology of early diagnostics, treatment and prophylaxis of dysplastic spine and joints diseases resulting in invalidism in young age. (2003-2006).
11.		Design, making and clinical using of new native artificial hip joint with sapphire-sapphire friction pair. (2003-2006)

Sytenko Institute of Spine and Joint Pathology National Academy of Medical Sciences of Ukraine

+38 (050) 554-10-10 +38 (063) 554-10-10 +38 (098) 554-10-10

Scientific Activities

Privileged research directions of the institution:

Fundamental Researches in Theoretical and Clinical Medicine

To study the possibilities of biotechnology for the correction of failed reparative osteogenesis to prevent nonunion and pseudoarthrosis

To investigate the pathogenetic relationship between hemostasis disorders and inflammatory-destructive changes in degenerative diseases, post-traumatic and combat injuries of large joints

To optimize the perioperative management of surgical interventions in patients with the consequences of combat injuries and orthopedic pathology combined with disorders of the cardiovascular and nervous systems

Applied Researches

To develop a complex of diagnostic-treatmental measures for internal-rotary contracture of the shoulder joint in children with obstetrical brachial plexus palsy of Duchenne-Erb

To improve the diagnosis and treatment of new compression fractures of the vertebrae of the thoracic and lumbar spine in patients with diffuse osteoporosis after vertebroplasty

To improve the diagnosis and treatment of degenerative diseases of the lumbar spine in military personnel (clinical and experimental study)

To develop a method of physical rehabilitation after endoscopic surgical treatment of herniated intervertebral discs of the lumbar spine for civilians and military personnel under the conditions of various clinical course variants and various external loads on the musculoskeletal system

To develop methods of rational treatment of gunshot fractures of the limbs based on the study of the tissue regeneration process

To develop methods for the reconstruction of post-resection and post-traumatic bone and joint defects in patients with primary tumors and traumatic injuries of the pelvic bones

To investigate the possibilities of osseointegrative limb prosthetics in patients with combat trauma consequences

To investigate the effectiveness of the use of biological therapy methods in the treatment of patients with defects of long bones after combat trauma

Fundamental researches in the theoretical and clinical medicine

«To study the possibilities of biotechnology for the correction of failed reparative osteogenesis to prevent nonunion and pseudoarthrosis». (2023-2025)

«To investigate the pathogenetic relationship between hemostasis disorders and inflammatory-destructive changes in degenerative diseases, post-traumatic and combat injuries of large joints» (2023-2025)

«To optimize the perioperative management of surgical interventions in patients with the consequences of combat injuries and orthopedic pathology combined with disorders of the cardiovascular and nervous systems» (2024-2026)

Applied researches

«To develop a complex of diagnostic-treatmental measures for internal-rotary contracture of the shoulder joint in children with obstetrical brachial plexus palsy of Duchenne-Erb » (2023-2025).

«To improve the diagnosis and treatment of new compression fractures of the vertebrae of the thoracic and lumbar spine in patients with diffuse osteoporosis after vertebroplasty (2024-2025)

«To improve the diagnosis and treatment of degenerative diseases of the lumbar spine in military personnel (clinical and experimental study)» (2024-2026)

«To develop methods of rational treatment of gunshot fractures of the limbs based on the study of the tissue regeneration process)» (2024-2026)

«To develop methods for the reconstruction of post-resection and post-traumatic bone and joint defects in patients with primary tumors and traumatic of the pelvic bones)» (2024-2026)

Fundamental researches in the theoretical and clinical medicine

To study the possibilities of biotechnology for the correction of failed reparative osteogenesis to prevent nonunion and pseudoarthrosis.

To investigate the pathogenetic relationship between hemostasis disorders and inflammatory-destructive changes in degenerative diseases, post-traumatic and combat injuries of large joints.

Applied researches

To study the features of functional disorders in the combined pathology of the lumbar spine and hip joint and to develop tactics and requirements for the surgical treatment of these patients.

To study the pathophysiological mechanisms of hemodynamic and neurological reactions caused by the type of anesthesia and intraoperative position of the patient’s body during spine surgery.

Develop tactics of rational spinal fusion for the treatment of patients with vertebral fractures of the thoracic spine.

To develop differentiated approaches of surgical treatment of patients with pelvic bone tumors.

Improve methods of surgical treatment of patients with degenerative-dystrophic diseases of the lumbar spine using the latest technologies.

To study the mechanisms of formation of immobilization contractures and to investigate the influence of low-frequency vibration on the restoration of joint function.

To develop a complex of diagnostic-treatmental measures for internal-rotary contracture of the shoulder joint in children with obstetrical brachial plexus palsy of Duchenne-Erb.

Fundamental researches in the theoretical and clinical medicine

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

To study the mechanisms of optimization of bone repair depending on the recipient’s age under the conditions of allogeneic bone grafts application in combination with mesenchymal stem cells and biologically active blood plasma factors.

Experimental study of bone tissue reaction and biomechanical properties of “implant-bone”system at application of innovative 3D-printed materials made of polilactide acid and trabecular titanium.

Applied researches

Develop a comprehensive approach to treatment of congenital pseudoarthrosis of the tibia and fibula in children.

To study the features of functional disorders in the combined pathology of the lumbar spine and hip joint and to develop tactics and requirements for the surgical treatment of these patients.

To study the pathophysiological mechanisms of hemodynamic and neurological reactions caused by the type of anesthesia and intraoperative position of the patient’s body during spine surgery.

Develop tactics of rational spinal fusion for the treatment of patients with vertebral fractures of the thoracic spine.

To develop differentiated approaches of surgical treatment of patients with pelvic bone tumors.

Improve methods of surgical treatment of patients with degenerative-dystrophic diseases of the lumbar spine using the latest technologies.

To study the mechanisms of formation of immobilization contractures and to investigate the influence of low-frequency vibration on the restoration of joint function.

Develop a set of medical and organizational measures to improve the system of medical care for victims of road accidents.

Fundamental researches in the theoretical and clinical medicine

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

To study the mechanisms of optimization of bone repair depending on the recipient’s age under the conditions of allogeneic bone grafts application in combination with mesenchymal stem cells and biologically active blood plasma factors.

Experimental study of bone tissue reaction and biomechanical properties of “implant-bone”system at application of innovative 3D-printed materials made of polilactide acid and trabecular titanium.

Applied researches

To study the main errors and complications of transpedicular fixation in spine surgery and to develop measures for their prevention and treatment.

To study the biomechanical features of the standing and walking function of a man after hip arthroplasty.

To work out the system of organizational arrangements, curative and preventive services, to decrease negative consequences of the traumatic and combat injuries of long bones.

Develop a comprehensive approach to treatment of congenital pseudoarthrosis of the tibia and fibula in children.

To study the features of functional disorders in the combined pathology of the lumbar spine and hip joint and to develop tactics and requirements for the surgical treatment of these patients.

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

To study the pathophysiological mechanisms of hemodynamic and neurological reactions caused by the type of anesthesia and intraoperative position of the patient’s body during spine surgery.

Develop tactics of rational spinal fusion for the treatment of patients with vertebral fractures of the thoracic spine.

To develop differentiated approaches of surgical treatment of patients with pelvic bone tumors.

Fundamental researches in the theoretical and clinical medicine

To explore etiopathogenesis and sanogenetic role of paravertebral muscles in development lumbar degenerative diseases.

To study the mechanisms of optimization of bone repair depending on the recipient’s age under the conditions of allogeneic bone grafts application in combination with mesenchymal stem cells and biologically active blood plasma factors.

Experimental study of bone tissue reaction and biomechanical properties of “implant-bone”system at application of innovative 3D-printed materials made of polilactide acid and trabecular titanium.

Applied researches

Develop a concept of treatment of traumatic and humidified burst bodies of the thoracal and lumbar spine.

Improve the diagnosis and surgical treatment of patients with hematopoietic and metastatic lesions of thoracic and lumbar spine.

To investigate the causes of development and improve the methods of prevention and treatment of contracture of the knee joints in gonarthrosis, as consequences of traumatic injuries and after total knee arthroplasty.

Develop methods bioreсonstrution defects of long bones and joints in the surgical treatment of bone tumors.

To study the main errors and complications of transpedicular fixation in spine surgery and to develop measures for their prevention and treatment.

To study the biomechanical features of the standing and walking function of a man after hip arthroplasty.

To work out the system of organizational arrangements, curative and preventive services, to decrease negative consequences of the traumatic and combat injuries of long bones.

Develop a comprehensive approach to treatment of congenital pseudoarthrosis of the tibia and fibula in children.

Fundamental researches in the theoretical and clinical medicine

To explore common links in the mechanism of pathogenesis of osteoporosis, osteoarthrosos and spine osteochondrosis for substantiation of approaches to improve the efficiency of diagnosis, prevention and treatment.